2020-12-06

Silent hypoxemia in a patient with severe SARS-CoV-2 pneumonia

Palman A. D., Andreev D. A., Suchkova S. A.

Sechenov Medical Journal

10.47093/2218-7332.2020.11.2.87-91

Patients with COVID-19 are typically characterized by severe lung injury with the development of acute respiratory failure. However, in some patients, subjective well-being may remain relatively satisfactory for a long time and, despite severe hypoxe...

2021-04-29

Studies and research design in medicine

Bulanov N. M., Blyuss O. B., Munblit D. B., Nekliudov N. A., Butnaru D. V., Kodzoeva K. B., Nadinskaya M. Yu., Zaikin A. A.

Sechenov Medical Journal

10.47093/2218-7332.2021.12.1.4-17

Adequate design is an essential condition for conducting a successful study. This review describes the most common types of research design in medicine. We discuss the differences between different types of observational and interventional studies, t...

2021-12-14

Basic principles of descriptive statistics in medical research

Bulanov N. M., Suvorov A. Yu., Blyuss O. B., Munblit D. B., Butnaru D. V., Nadinskaia M. Yu., Zaikin A. A.

Sechenov Medical Journal

10.47093/2218-7332.2021.12.3.4-16

Descriptive statistics provides tools to explore, summarize and illustrate the research data. In this tutorial we discuss two main types of data - qualitative and quantitative variables, and the most common approaches to characterize data distributio...

2020-12-06

Features of the management of cancer patients during the COVID-19 pandemic

Sekacheva M. I., Rusanov A. S., Fatyanova A. S., Boroda A. M., Istranov A. L., Rusanov S. N., Babayeva Yu. V., Poddubskaya E. V.

Sechenov Medical Journal

10.47093/2218-7332.2020.11.2.62-73

Novel coronavirus infection, causing COVID-19, is not fully controlled for today. In periodicals, there are often reports of a high risk of severe complications in cancer patients during the development of COVID-19. The review presents information fr...

2020-03-30

Peripartum cardiomyopathy (clinical case)

Ilina Yu. V., Fedorova T. A., Loshchits N. V., Vanhin V. V.

Sechenov Medical Journal

10.47093/2218-7332.2020.11.1.71-77

Introduction. Peripartum cardiomyopathy (PPKMP) is a rare cause of heart failure (CHF) in healthy women during pregnancy and within 5 months after delivery.Case report. A 33-year-old female patient, a native of Tajikistan, first developed shortness o...

2020-12-28

Risk factors for recurrence of ovarian endometriomas after surgical treatment: retrospective cohort study

Kachalina T. S., Bogatova M. E., Kuznetsov S. S., Lazukin V. F.

Sechenov Medical Journal

10.47093/2218-7332.2020.11.4.60-71

Aim. To identify risk factors for recurrence of ovarian endometriomas after surgical treatment.Materials and methods. The retrospective cohort study included 82 patients operated on for the first time for ovarian endometriomas, the follow-up period w...

2020-03-30

Depressive disorder and quality of life in patients with cerebral microangiopathy

Vorob’eva O. V., Fateeva V. V.

Sechenov Medical Journal

10.47093/2218-7332.2020.11.1.49-58

The association between depressive disorder and quality of life of middle-aged patients with cerebral microangiopathy has not been fully investigated.Aim. Study the association between the depression level and quality of life (QOL) in patients with c...

2020-12-06

Diagnostic value of lung ultrasound versus chest CT in COVID-19

Petrikov S. S., Popova I. E., Abuchina V. M., Muslimov R. Sh., Khamidova L. T., Popugayev K. A., Kokov, L. S.

Sechenov Medical Journal

10.47093/2218-7332.2020.11.2.5-18

Lung ultrasound demonstrates a high diagnostic value in the assessment of lung diseases.Aim. To determine the diagnostic accuracy of lung ultrasound compared to chest computed tomography (CT) in the diagnosis of lung changes in COVID-19. Materials an...

2021-10-25

Statistical hypothesis testing: general approach in medical research

Suvorov A. Yu., Bulanov N. М., Shvedova A. N., Tao E. A., Butnaru D. V., Nadinskaia M. Yu., Zaikin A. A.

Sechenov Medical Journal

10.47093/2218-7332.2022.426.08

Statistical hypothesis testing is one of the key steps in modern medical research. Initially, scientists formulate a research hypothesis based on which the statistical hypothesis is then developed and statistically tested. This review provides the nu...

2023-03-30

Basic aspects of meta-analysis. Part 1

Suvorov A. Yu., Latushkina I. V., Gulyaeva K. А., Bulanov N. M., Nadinskaia M. Yu., Zaikin A. A.

Sechenov Medical Journal

10.47093/2218-7332.2023.14.1.4-14

   Meta-analysis is one of the concepts of scientific methodology, and is a frequent but optional component of systematic reviews of empirical research. It joins the results of several scientific studies and tests one or more interrelated scientific ...

2020-12-06

Complex mechanism of COVID-19 development

Bolevich S. B., Bolevich S. S.

Sechenov Medical Journal

10.47093/2218-7332.2020.11.2.50-61

Coronavirus infection (COVID-19) is an acute viral disease, which affects all vital organs and is caused by an RNA-genomic virus of the genus Betacoronavirus of the family Coronaviridae. This virus (SARS-CoV-2) enters the body through the respiratory...

2022-10-28

Chronic heart failure with preserved ejection fraction: optimal therapy. Literature review

Kuzmenko A. A., Sokolova A. A., Napalkov D. A.

Sechenov Medical Journal

10.47093/2218-7332.2022.13.3.4-13

The literature review discusses approaches to the treatment of patients with chronic heart failure and preserved ejection fraction (EF>50) – HFpEF. The impact of various groups of drugs on the prognosis and quality of life of patients in this coho...